Areas of Interest

• Hepatology
• Gastroenterology

Educational and Career Experiences

Masao Omata, MD, has made an effort to revitalize the APASL (Asian Pacific association for the study of the Liver) with Dr. S. Sarin and others for the last 10 years. He is a Co-Editor in Chief of the Hepatology International, an official journal of APASL. He graduated from Chiba University School of Medicine (Dr. Okuda), and continued his training at Yale University (Dr. G Klaskin) and in the Liver Unit at University of Southern California (Dr. RL Peters). After 6 years in US, he returned to the Department of Medicine at Chiba University in 1989, and started molecular biological study on Hepatitis B virus.

In 1992, he became Chairman of Second Department of International Medicine at University of Tokyo, Japan and then subsequently became chairman of Department of Gastroenterology. Under his leadership, the Department of Gastroenterology had become one of the foremost centers in its field.

Now, he is the president of the two hospitals at Yamanashi, west of Tokyo, where, although scenic place with Mt. Fuji, hepatitis virus infection is epidemic and his homeland. He and his colleague have published 1,164 articles in English Literature including, NEJM 5, Lancet 6, Ann Int Med 6, Hepatology 59, Gastroenterology 43. The total impact factor is 6,723 and 42,844 citations with H-index of 104 as of July 1st, 2017.

Honors and Awards

• 1999 Outstanding Service to the AGA (American Gastroenterological Association)
• 2003 The Japan Society of Hepatology Award
• 2003 Chiba University Achievement Award
• 2017 JSGE Research Award (The Japanese Society of Gastroenterology)

Educational and Career Experiences

• 1975-1981 MD, Nihon University School of Medicine
• 1981-1985 Graduate School of Medicine, Nihon University School of Medicine
• 1985-1993 Resident in third Department of Internal Medicine, Nihon University School of Medicine
• 1993-1995 Assistant, Third Department of Internal Medicine, Nihon University School of Medicine
• 1995-2003 Lecturer, Third Department of Internal Medicine, Nihon University School of Medicine
• 2003-2007 Assistant professor, Third Department of Internal Medicine, Nihon University School of Medicine
• 2007- Professor ＆Chairman, Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine
• 2017-2019 Vice Director, NIHON UNIVERSITY ITABASHI HOSPITAL
• 2019- Director, NIHON UNIVERSITY ITABASHI HOSPITAL

Membership of Academic Societies

• American Gastroenterological Association, international Member
• International Association for the Study of the liver
• Asian Pacific Association for the Study of the liver
• Japanese Society of Internal Medicine
• Japanese Society of Gastroenterology
• Japan Society of Hepatology
• Japanese Society of Gastroenterological Cancer Screening
• Japanese Association for Cancer Detection and Diagnosis
• Japan Society for Biomedical Research on Trace Elements
• Japanese Society of Parasitology
• Japan Gastroenterological Endoscopy Society
• Japanese Society of Nutritional Assessment
• Japanese society of digestion and absorption

Major Field of Interest

• Viral Hepatitis, Pathology of liver

Areas of Interest

• Liver surgery; Hepatocellular carcinoma; Systematic liver resection; Caudate lobe resection; Colorectal metastases.

Educational and Career Experiences

• 1974-1980: Nihon University School of Medicine
• 1987-1995: Liver Surgery, National Cancer Center Hospital
• 1995-2001: Associate Prof., Hepato-Biliary-Pancreatic Surgery, University of Tokyo
• 2001 - - - - : Prof., Digestive Surgery, Nihon University
• 2014 - - - - : Dean, Nihon University School of Medicine

Honors and Awards

• 2001: Oda's Award from Japanese Society of Hepatology
• 2002: Medical Research Award from Tokyo Medical Association
• 2008: International Medical Communication Award
• 2010: Ariga's Award from Nihon University Medical Association
• 2016: Art of Year Award from Jap Gastroenterol Surgery
• Academic activity: 506 English papers including 7 papers in The Lancet

Areas of Interest

• Viral Hepatitis, Autoimmune Liver Diseases, Innate Immunity, Hepatocarcinogenesis

Educational and Career Experiences

• 1991 M.D., cum laud, Niigata University School of Medicine, Niigata, Japan
• 1999 Ph.D. (Dr. of Medical Science), Graduate School of Medicine, Chiba University, Chiba, Japan
• 1991-2000 Medical Staff in Internal Medicine, Chiba University, Chiba, Japan
• 2000-2005 Assistant Professor, Safety and Health Organization (Health Sciences Center), Chiba University, Chiba, Japan
• 2005-2008 Faculty, Dept. Pathology, Saint Louis University, St. Louis, MO, USA
• 2008-2012 Associate Professor, Dept. Medicine and Clinical Oncology, Chiba University, Graduate School of Medicine, Chiba, Japan
• 2012-2017 Associate Professor, Dept. Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, Chiba, Japan
• 2017- Associate Professor, Division of Gastroenterology and Hepatology, Dept. Medicine, Nihon University, School of Medicine, Tokyo, Japan
• Editorial Board: Hepatology International, PLoS ONE, International Journal of Molecular Sciences, Canadian Journal of Gastroenterology and Hepatology, World Journal of Gastroenterology, Journal of Clinical and Translational Hepatology, OBM Hepatology and Gastroenterology (Associate Editor)

Honors and Awards

Awards:

• (1) First JSH Single Topic Conference "Therapy of Viral hepatitis and Prevention of Hepatocellular Carcinoma" at Mt. Fuji, 2002.11.14. Award.
• (2) Asian Pacific Association for the Study of the Liver, 14th Biennial Conference, Young Investigator Award. Asian Pacific Association for the Study of the Liver, 14th Biennial Conference, New Delhi, India, 2004.12.13.
• (3) American Society for Virology 2006 Postdoctoral Fellow Travel Award. American Society for Virology, 25th annual meeting, University of Wisconsin-Madison, Madison, WI, USA, 2006.7.15., etc

Areas of Interest

• Viral hepatitis
• Fatty liver
• Liver cancer

Educational and Career Experiences

• 1979 Graduate from Chiba University School of Medicine (MD)
• 1987 Graduate from Chiba University Graduate School of medicine (PhD in Medicine)
• 1979-1982 Resident, First Department of Internal Medicine, Chiba University
• 1982-1990 Research Fellow, First Department of Internal Medicine, Chiba University
• 1990-1996 Assistant Professor, First Department of Internal Medicine, Chiba University
• 1996-2007 Senior Lecturer, First Department of Internal Medicine, Chiba University
• 2007-2012 Associate Professor, First Department of Internal Medicine, Chiba University
• 2012- Professor and Director, Safety and Health Organization, Chiba University

Awards/Honors

• 1988 Research Award from Japan Society of Hepatology
• 1989 Research Award from Viral Hepatitis Research Foundation of Japan

EDUCATION:

• 1999 Ph.D. (Dr. of Medical Science), Division of Gastroenterology and Hepatology Department of Medicine, Nihon University, School of Medicine , Japan
• 1988 M.D., Nihon University, School of Medicine, Japan

Professional Training and Employment:

• 2020.4- Visiting Professor of Medicine, Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University, School of Medicine
• 2015.4- Professor of Medicine, Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University, School of Medicine
• 2008.5- Associate Professor, Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University, School of Medicine
• 2005.4- General Manager of Medical Department, Division of Gastroenterology, Social insurance Yokohama Central Hospital
• 2001.6- General Manager of Internal Medicine Department, Mitsuwadai General Hospital
• 1996.12- Head of Medical Department, Division of Gastroenterology, Social insurance Yokohama Central Hospital
• 1993.6- Medical Staff in Hepatology, National Public Service Mutual Aid Toranomon Hospital
• 1988 Passed the Examination of National Board, Japan

EDUCATION:

• 1988 Graduated from Nihon University, Medical school

LICENSURE and CERTIFICATION:

• National Board of Medicine, Registration No. 316469
• Board Certified Fellow of the Japan Society of Ultrasonics in Medicine No.1287
• Senior Fellow of the Japan Society of Ultrasonics in Medicine No.715
• Board Certified Member of the Japanese Society of Internal Medicine No. 84779
• Board Certified Hepatologist of the Japan Society of Hepatology No. 4963
• Board Certified Gastroenterologist of the Japanese Society of Gastroenterology No. 24764
• Board Certified Gastroenterologist of the Japan Gastroenterological Endoscopy Society No. 20010126
• Board certified member of the Japanese Society of Gastroenterological Cancer Screening No. 1574

MEMBERSHIPS:

• The Japan Society of Ultrasonic in Medicine
• The Japanese Society of Internal Medicine
• The Japan Society of Hepatology
• The Japanese Society of Gastroenterology
• The Japan Gastroenterological Endoscopy Society
• The Japanese Society of Gastroenterological Cancer Screening
• The Japanese Diabetes Society

MAJOR RESEARCH INTERESTS:

• Diagnostic imaging of a gastroenterology
• Ultrasonic diagnosis

Areas of interest

• Hepatocellular carcinoma, Liver fibrosis

Educational and Career Experiences

• Oita University MD 03/2000 Medicine
• The University of Tokyo PhD 03/2010 Gastroenterology

• 2000-2002 Resident in Internal Medicine, Saga University, Saga, Japan
• 2002-2004 Resident in Internal Medicine, Saga Prefectural Hospital, Saga, Japan
• 2004-2010 Clinical Fellow in Gastroenterology, The University of Tokyo Hospital, Tokyo, Japan
• 2010-2011 Research Fellow, Beth Israel Deaconess Medical Center, Boston, MA, USA
• 2011-2014 Research Fellow, Vanderbilt University Medical Center, Nashville, TN, USA
• 2014-2019 Research Assistant Professor, Vanderbilt University Medical Center, Nashville, TN, USA
• 2019-2020 Clinical Fellow in Gastroenterology, Nihon University School of Medicine, Tokyo, Japan
• 2020-present Assistant Professor in Gastroenterology, Nihon University School of Medicine, Tokyo, Japan

Honors and Awards

• 2005 Poster of Distinction-DDW
• 2009 Taisho Toyama Award
• 2010 Young Investigator Award-APASL
• 2018 Poster of Distinction-AASLD

Areas of Interest

• Viral hepatitis
• Hepatocellular carcinoma
• Autoimmune liver diseases: PBC, AIH, PSC

Educational and Career Experiences

• 1989-1992: Research Fellow at 1st Dept of Intern Med, Chiba Univ Sch Med
• 1992-1993: Research Fellow at Virology Div, Natl Cancer Ctr Res Inst
• 1993-1998: Research Fellow at Dept Gastroenterology, Fac Med, Univ Tokyo
• 1999-2008: Research Assoc at Dept Gastroenterology, Grad Sch Med, Univ Tokyo
• 2008-2008: Project Lecturer at Dept Gastroenterology, Grad Sch Med, Univ Tokyo
• 2008-2013: Project Assoc Prof & Director at Unit of Disease Ctrl Genome Med, Inst Med Sci, Univ Tokyo
• 2013-2017: Assoc Prof and Director at Div Advanced Genome Med, Inst Med Sci, Univ Tokyo
• 2017-: Prof & Chair at Dept Gastroenterology, Grad Sch Med, Chiba Univ

Honors and Awards

• Research Award from Viral Hepatitis Research Foundation of Japan
• Research Award from The Institute for Adult Diseases, Asahi Life Foundation
• Crown Award from Japan Society of Hepatology
• Academic Award from Inohana Alumni Association
• Research Award from Foundation for Advancement of International Science Forum

Professor Norifumi Kawada was graduated with M.D. degree in 1986 from Osaka City University Medical School. He obtained his Ph.D. degree from Osaka City University in 1991. From 1991 to 1992, Prof. Kawada trained as a Visiting Scientist, Institute of Biochemistry, Freiburg University. And then, from 1993 to 2006, he worked as a Research Associate, Assistant Professor, and Associate Professor in Osaka City University Graduate School of Medicine.

He was promoted as a professor of Osaka City University Graduate School of Medicine in 2007. His research interests are biology of stellate cells, liver fibrosis, and carcinogenesis. He is a reviewer and member of editorial board of several scientific journals. Prof. Kawada was Visiting Scientist, Department of Hepatology, Florence University in 2004, and from 2015, he is a visiting Professor of University College London (UCL). He assumes a fellow of American Association for the Study of Liver Diseases (AASLD) in 2015.

EDUCATION

• 1993 M.D. University of Hokkaido, Sapporo, Japan.
• 1996-2000 Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
• 2000 Ph.D Dissertation: Mechanism of Helicobacter pylori virulence.

PROFESSIONAL EXPERIENCE

• 1993-1994 Resident, Tokyo University Hospital
• 1994-1995 Resident, Japan Red-cross Medical Center
• 1995-1996 Medical Doctor, Dept of Gastroenterology, Tokyo University Hospital
• 2000-2001 Medical Doctor, Dept of Gastroenterology, Tokyo University Hospital
• 2001-2005 Postdoctoral Fellow, Dept of Pharmacology, University　of California, San Diego (Dr. Michael Karin), CA, U.S.A.
• 2005-2008 Chief, Division of Gastroenterology, Institute of Adult Diseases, Asahi Life Foundation, Tokyo, Japan.
• 2008-2010 Research Associate, Dept of Gastroenterology, University of Tokyo
• 2010-present Professor and Chairman, Department of Gastroenterology, Yokohama City University, Yokohama, Japan.

SELECTED PUBLICATIONS

1. Maeda S, Yoshida H, Ogura K, et al. H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells. Gastroenterology 119:97-108,2000.
2. Maeda S, Kamata H, Luo JL, et al. IKKb couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121:977-90,2005.
3. Maeda S, Hikiba Y, Sakamoto K, et al. IKKβ/NF-κB Activation Controls the Development of Liver Metastasis via IL-6 Expression. Hepatology 50:1851-60,2009.
4. Nakagawa H, Hikiba Y, Maeda S, et al. Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis. Proc Natl Acad Sci U S A, 111(3):1090-5,2014.

Education / Post Graduate Training

College/University

• 1985-1991 MD, Teikyo University School of Medicine
• May 2007 PhD Gastroenterology Tokyo University School of Medicine #16800

Residency

• 1991-1992 Tokyo Metropolitan Tama Medical Center, Tokyo, Japan
• 1992-1993 Tokyo University School of Medicine, Tokyo, Japan
• 1993-1995 General Hospital National Health Insurance Asahi Central Hospital, Chiba, Japan

Medical Licensure

• 1991 Full Medical License (Japan) #340521

Board Certification

• Jan 1999 Fellow of the Japanese Society of Gastroenterology #29994
• Sep 2005 Fellow of the Japanese Society of Internal Medicine #85489
• Apr 2010 Fellow of the Japanese Board of Cancer Therapy #09100064

Present Position or Academic Rank

• 2008-present Assistant Professor, Gastroenterology, Tokyo University School of Medicine
• 2011-present Assistant Professor, Gastroenterology Kagawa University School of Medicine
• 2016-present Professor Gastroenterology, Teikyo University School of Medicine Chiba Medical Center

Previous Professional Positions and Appointments

• 1995-1998 Staff Physician, Internal Medicine (II), Tokyo University School of Medicine, Tokyo, Japan
• 1998-2002 Staff Physician, Gastroenterology, Tokyo University School of Medicine
• 2002-2016 Division Chief, Department of Internal Medicine, Division of Hepatology, Kyoundo Hospital
• 2005-2016 Director, Sasaki Foundation
• 2006-2016 Director, Kyoundo Hospital, Tokyo, Japan
• 2009-2016 Assistant Professor in Gastroenterology Teikyo University School of Medicine
• 2012-2015 Assistant Professor, Gastroenterology Yamanasi University School of Medicine

Honors and Awards

• 2009 Fellowship Award from the Foundation for Promotion of Cancer Research

Professional and Society Membership

• 1991-present The Japanese Society of Internal Medicine
• 1993-present The Japanese Society of Gastroenterology
• 1993-present The Japanese Society of Hepatology
• 2007-present The Asian Pacific Association of the Study of the Liver

Areas of Interest

• Abdominal Imaging, Interventional oncology (minimally invasive therapy, such as radiofrequency ablation, microwave ablation)

Educational and Career Experiences

Education:

• 1982, M.D. University of Tokyo, Faculty of Medicine

Professional Career:

• 2012-present:Professor, Department of Gastroenterology, Juntendo University
• 2004-2012:Associate Professor, Department of Gastroenterology, University of Tokyo
• 1997-2004:Assistant Professor, Department of Gastroenterology, University of Tokyo
• 1996-1997:Director, Department of Gastroenterology, Chigasaki Municipal Hospital, Kanagawa
• 1992-1996: Assistant Professor, Department of Medicine(Ⅱ), University of Tokyo
• 1986-1992:Instructor, Department of Medicine (Ⅱ), University of Tokyo
• 1983-1986:Resident in Medicine & Clinical Fellow in Gastroenterology, Mitsui Memorial Hospital, Tokyo
• 1982-1983:Resident in Medicine, University of Tokyo,Tokyo

Honors and Awards

• 2015 ACTA (Asian Conference on Tumor Ablation)
  Presidential Award

Areas of Interest

• Autoimmune Liver Diseases
• Viral hepatitis
• Liver Immunology and Genetics

Prof. Atsushi Tanaka was graduated with M.D. degree in 1988 from the University of Tokyo, Japan. After spending three years as residency at St. Luke's International Hospital in Tokyo, he started his career as a researcher in liver diseases with a main focus on autoimmune liver diseases and viral hepatitis. He obtained his Ph.D. degree from the University of Tokyo in 1996, and thereafter he stayed at the University of California, Davis since 1996 to 1999 as a visiting scholar with M. Eric Gershwin, M.D., where he elucidated T cell mechanisms involved in the pathogenesis and progression of primary biliary cholangitis (PBC).

Coming back to Japan in 2000, he rose through the academic ranks to become a Professor of Medicine at the Teikyo University School of Medicine in 2011. His area of expertise is autoimmune liver diseases, especially PBC, PSC and AIH. He has authored 100 peer-reviewed manuscripts devoted to these topics. He has provided exceptional leadership to Japanese hepatology, including ongoing service as Secretary-General of the Drafting Committee for Hepatitis Management Guidelines of the Japan Society of Hepatology (JSH) and play a central role in publishing as well as revising the JSH Guidelines for the Management of HBV/HCV infection. Currently he also serves as a Secretary-General of the Intractable Hepatobiliary Disease Study Group supported by the Ministry of Health, Labor and Welfare of Japan, and is one of the leaders for research of autoimmune liver diseases in Japan.

Professor Yoshiyuki Ueno is currently Professor of Medicine, Head of Division of Gastroenterology and Hepatology and Vice Director of Yamagata University Hospital. He is the course director of PhD course in Gastroenterology, Postgraduate School of Medicine Yamagata University. Professor Ueno has been engaged in the field of Hepatology since after his graduation of medical school at Tohoku University in 1987. After obtaining PhD degree in 1991, he had been a research fellow at Mayo Clinic, Rochester, USA. Since after his return to Japan, he continues to work as an academic researcher. Currently, he is an associate editor of Hepatology Research, Hepatology International, and Seminars in Liver Diseases. He has been actively involved in more than 20 international trials on antiviral treatment of chronic hepatitis B and C. He is one of the AASLD inaugural Fellow, and first Japanese hepatologist to become both AASLD and AGA Fellow. He has been involved in several steering committees of academic societies. He has received numerous local, national and international research awards. He has published more than 250 peer-reviewed papers in international journals including 2 in PNAS, 9 in Gastroenterology, 22 in Hepatology, 3 in J Hepatol, 22 in AJP.

Areas of Interest

• Viral hepatitis, Anti-viral treatment, Hepatocellular Carcinoma (HCC), Risk factors for development of HCC

Educational and Career Experiences

• 1984: Graduated from Nagasaki University School of Medicine
• 1984-1988:（Post-graduate Training） 1st Department of Medicine, Nagasaki University
• 1988-: Clinical Research Center, Nagasaki Medical Center
• 2002-2012: Director, Department of Therapeutic Research, Clinical Research Center, Nagasaki Medical Center
• 2004-: Professor, Division of Viral Hepatitis, Department of Hepatology, Nagasaki University Graduate School of Biomedical Sciences,
• 2012-: Director General, Clinical Research Center, Nagasaki Medical Center
• 2013-2017: APASL Executive Counci
• 2017.Apr:President of APASL-STC 2017 Nagasaki

Educational and Career Experiences

• 1975 Graduated Chiba University School of Medicine
• 1975-1978 Trainee in Chiba University Hospital (Prof. K Okuda)
• 1978-1980 Royal Free Hospital, London (Prof. S Schelock, Prof. BH Billing)
• 1980-1985 Fellow (Chiba University)
• 1984 Fox Chase Cancer Center, Philadelphia (Dr. J Summers)
• 1985 Degree of Dr. of Medical Science
• 1985-1994 Assistant Professor, Chiba University
• 1994-2006 Lecturer in Medicine, Chiba University
• 2006-2016 Director and Professor of Medicine, Chiba University
• 2008-2014 Secretary General of APASL
• 2013-2015 Dean, Chiba University School of Medicine
• 2015-2016 President of APASL 2016 Tokyo
• 2016 - President, Japan Community Health Care Organization (JCHO) Funabashi Central Hospital

Main field of Interest

• Hepatitis and Hepatocellular Carcinoma

Areas of Interest

• NAFLD/NASH, Viral hepatitis (HBV/HCV), Cirrhosis, HCC, Virology, Genetics and Epigenetics.

Educational and Career Experiences

• 1989-1995: M.D, Gifu University School of Medicine.
• 2004: Ph.D, Gifu University School of Medicine.
• 1995-2000: Resident, Toranomon Hospital. Department of Internal Medicine.
• 2000-2012: Medical staff, Toranomon Hospital, Department of Hepatology.
• 2012-Present: Chief Physician, Toranomon Hospital, Department of Hepatology.
• 2015-Present: Visiting lecturer, Fujita Health University, Department of Liver, Biliary Tract and Pancreas Diseases.1981 Medical Doctor's license in Japan

Guideline Committee Membership

Clinical Practice Guideline 2020 for NAFLD/NASH, The Japanese Society of Gastroenterology.

Clinical Guide 2020 for NASH/NAFLD, The Japan Society of Hepatology.

Honors and Awards

• 2006: Best Performance Award, The Japan Society Hepatology (East).
• 2007: Research Award, Liver Forum in Kyoto.
• 2007: Research Award, Liver Forum (East).
• 2008: Research Award, Hamanako Symposium.
• 2011: MSD Award, The Japan Society Hepatology.
• 2014: Research Award, Viral Hepatitis Research Foundation of Japan.
• 2015: Research Award, Liver Forum in Kyoto.
• 2016: Outstanding Performance Award, JDDW 2016 Kobe.
• 2018: Presidential poster of distinction, AASLD 2018 San Francisco.

Patents

• Patent No. 4794944: Methodology for the prediction of treatment efficacy to interferon and ribavirin combination therapy in patients infected with HCV.
• Patent No. 5960509: Methodology for the prediction of hepatocarcinogenesis in patients infected with HCV.

Areas of Interest

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Educational and Career Experiences

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Honors and Awards

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Educational and Career Experiences

• 2003- Professor, First Department of Internal Medicine, University of Yamanashi, Yamanashi, Japan
• 2000 Associate Professor, Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan
• 1993 Assistant Professor, Second Department of Internal Medicine, Tokyo Medical and Dental University, Tokyo, Japan
• 1990 Clinical fellow, Second Department of Internal Medicine, Tokyo Medical and Dental University, Tokyo, Japan
• 1987 Assistant Professor, Department of Gastroenterology, Kanazawa Medical University, Ishikawa, Japan
• 1984 Resident, Second Department of Internal Medicine, Tokyo Medical and Dental University, Tokyo, Japan
• 1984 Tokyo Medical and Dental University

Honors and Awards

• 1990 Sherlock Prize, International Association of the Study of Liver
• 1991 Research Award of Japanese Society of Internal Medicine
• 1992 Research Award of Japanese Society of Gastroenterology
• 1996 Research Award of the Viral Hepatitis Foundation
• 2016 Research Award of Japan Society of Hepatology

Membership in Professional Societies

• Japanese Society of Internal Medicine
• Japanese Society of Gastroentelogy
• Japan Society of Hepatology
• Japan Gastroenterological Endoscopy Society

Areas of Interest

• Hepatology Gastroenterology Ultrasonics in Medicine

Educational and Career Experiences

• 1983-1985 Department of Internal Medicine Hyogo College of Medicine
• 1985-1986 Department of Internal Medicine Fujimoto Hospital
• 1986-2000 Department of Internal Medicine Hyogo College of Medicine
• 2000-2003 Department of Gastroenterology Tokyo Medical University
• 2003-2005 Vising Clinical Professor of Department of Medical Imaging University of Toronto Toronto General Hospital　Visiting Professor of Department of Medical Biophysics University of Toronto Sunnybrook Health Sciences Centre
• 2005- present Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine and Ultrasound Imaging Center, Hyogo College of Medicine.
• 2008- Professor of Department of Hepatolo-biliary-pancreatic Medicine,Head of the Section of Ultrasound at Ultrasound Imaging Center, Hyogo College of Medicine.
• 2020- Professor of Division of Gastroenterology and Hepatology, Department of Internal Medicine, Liver Disease Center, Diversity Promotion Office, Hyogo College of Medicine.

Honors and Awards

• May2002 American Institute of Ultrasound in Medicine Award
• Oct2002 The 10th United European Gastroenterology Week Award
• MAY2007 The Japan Society of Hepatology Hepatology Research award
• May2020 The Japan Society of Ultrassonics in Medicine Award 19th Matsuo Award

Areas of Interest

• Pathogenesis of liver diseases (oxidative stress, mitochondrial biology, iron metabolism)
• Carcinogenesis of HCC (microenvironment, metabolic reprogramming)

Educational and Career Experiences

• 1982: Graduate from Yamaguchi University School of Medicine
• 1996: Overseas researcher of Ministry of Education and Visiting fellow in Institute of Virology, University of Glasgow
• 2005: Professor of Laboratory Sciences, Yamaguchi University Graduate School of Medicine
• 2008: Professor of Hepatology and Pancreatology, Kawasaki Medical School

Honors and Awards

• 1996: Uehara Memorial Foundation Postdoctoral Fellowship Award
• 2004: Yamaguchi University School of Medicine New Frontier Project, Fellowship Award
• 2006: Liver Forum Fellowship Award
• 2007: Japanese Society of Hepatology Shering Plough Award
• 2008: Ryobi Teien Memory Foundation Fellowship Award

Dr. Koike obtained his M.D. degree from The University of Tokyo in 1980. From 1986 to 1989, he worked in the National Cancer Institute, Bethesda. In 2004, he has been appointed as the Professor and Chairman of Department of Infectious Diseases, and, in 2009, has been appointed as the Professor and Chairman of Department of Gastroenterology, The University of Tokyo. He has been the Director General of The Japan Society of Hepatology since 2010, and was Director General of The Japanese Society of Internal Medicine from 2013 to 2016. He is a board-certified hepatologist and board-certified gastroenterologist. He has been chiefly working on the clinical practice on viral hepatitis B & C, NASH, and diagnosis and treatment of hepatocellular carcinoma. He has published more than 700 original articles.

Educational and Career Experiences

• 1980 Graduated, Faculty of Medicine, The University of Tokyo, Japan.
• 1980-83 First Department of Internal Medicine, The University of Tokyo Hospital, Japan.
• 1984-86 Research Fellow, Department of Enteroviruses, National Institute of Health, Japan.
• 1986-88 Visiting Fellow, Laboratory of Molecular Virology, National Cancer Institute, NIH, Bethesda, MD, USA.
• 1988-89 Research Fellow, Laboratory of Virology, J. Holland Research Institute, American Red Cross, Rockville, MD, USA.
• 1989-91 Instructor, First Department of Internal Medicine, Faculty of Medicine, The University of Tokyo, Japan.
• 1991-97 Assistant Professor, First Department of Internal Medicine, Faculty of Medicine, The University of Tokyo, Japan.
• 1997-98 Lecturer, First Department of Internal Medicine, Faculty of Medicine, The University of Tokyo, Japan.
• 1998-2004 Associate Professor, Department of Infectious Diseases, Internal Medicine, Graduate School of Medicine, The University of Tokyo, Japan.
• 2004-09 Professor and Chairman, Department of Infectious Diseases, Internal Medicine, Graduate School of Medicine, The University of Tokyo, Japan.
• 2009-present Professor and Chairman, Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Japan.

Membership

• Director General, The Japan Society of Hepatology (JSH) (2010〜)
• Director General, The Japanese Society of Internal Medicine (2013〜2016)
• Director, The Japanese Society of Gastroenterology (JSGE) (2012〜)
• Director General, The Japanese Society of Molecular Medicine (2016〜)
• Councilor, The Japanese Cancer Association
• Councilor, The Japanese Association for Infectious Diseases
• The Japanese Society for Virology

Editorial experiences

• Journal of Hepatology Associate Editor (2005-2009)
• Liver International Associate Editor (2014-)
• Hepatology Editorial Board (2004-2007)
• Journal of Gastroenterology (Official journal of JSGE)
• Deputy Editor-in-Chief (2005-2007),
• Associate Editor (2001-2005)
• Hepatology Research (Official journal of JSH)
• Deputy Editor-in-Chief (2008-2010),
• Associate Editor (2004-2008)
• Journal of Gastroenterology and Hepatology Editorial Board (2010-)

Areas of Interest

• Comparative liver inflammology
• Autoimmune liver disease
• iver carcinogenesis

Educational and Career Experiences

• 1989.3 Degree of Medicine, Kyushu University, School of Medicine, Japan
• 1989.6-1990.5: Junior Resident, Internal Medicine, Kyushu University Hospital, Japan
• 1990.6-1991.5: Junior Resident, Internal Medicine, Kyushu Koseinennkin Hospital, Japan
• 1991.6-1993.9: Research Fellow, Cancer Preventive Division, National Cancer Center Research Institute, Japan
• 1993.10-1997.5: Research Fellow Saitama Cancer Center Research Institute, Japan
• 1997.6-1998.5: Clinical Fellow,1st Department of Internal Medicine, Kyushu University Hospital, Japan
• 1998.6-2000.2: Clinical Fellow, 3rd Department of Internal Medicine Oita Red Cross Hospital, Japan
• 2000.3-2002.11: Post Doctoral Research Associate, Department of Laboratory Medicine, Weill Medical College of Cornell University, U.S.A.
• 2003.1-2014.3: Division Chief, Division of Bioregulation, Clinical Research Center, National Hospital Organization Nagasaki Medical Center, Japan
• 2014.4- Current position

Honors and Awards

• 2015-, Honorary professor of Kazakhstan National Medical University

• 1977 M.D., Nagoya University School of Medicine, Nagoya, Japan.
• 1977-1982 Resident, Department of Internal Medicine, 0gaki Municipal Hospital, Ogaki, Japan.
• 1982-1984 Resident, Section of Hepatology, Second Department of Internal Medicine, Nagoya University School of Medicine, Nagoya, Japan.
• 1984- Department of Gastroenterology and Hepatology, 0gaki Municipal Hospital, Ogaki, Japan.
• 2000- Medical Director, Department of Gastroenterology and Hepatology, 0gaki Municipal Hospital, Ogaki, Japan.
• 2011- Executive vice president, 0gaki Municipal Hospital, Ogaki, Japan.
• 2016- Clinical professor, Nagoya University School of Medicine, Nagoya, Japan.
• 2018- Professor, Nursing, Ogaki Women's College.
• 2018- Visiting professor, Suzuka University of Medical Science.
• 2019- Professor, Faculty of Nursing, Gifu Kyoritsu University

Speciality and Research Field of Interest

• Hepatology
• Medical Oncology
• Interventional Radiology
• Treatment of hepatic Malignancies
• Viral hepatitis

Scientific society

• The Japan Society of Internal Medicine, Specialist, Supervisor, Service member, Sub-committee chair on ultrasound diagnostic criteria for fatty liver
• The Japan Society of Hepatology, Specialist, Supervisor
• The Japanese Society of Gastroenterology, Specialist, Supervisor
• Japan Gastroenterological Endoscopy Society, Specialist, Supervisor
• The Japanese Society of Internal Medicine, Certifying physician
• Liver Cancer Study Group of Japan, Special member

Internal scientific papers

• 290

Areas of Interest

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Educational and Career Experiences

• ############################

Honors and Awards

• ############################

Areas of Interest

• Hepatology

Education and Carrier

• 1990: M.D., Kagawa University School of Medicine
• 1994: Ph.D. (Doctorate of Medical Science), Kagawa University, Department of Internal Medicine
• 1966-1998: Visiting researcher. University of Tokyo, Department of Internal Medicine
• 2005-2007: Assistant professor, Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University
• 2008-present: Professor and Chairman, Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University

Current research projects

1. Diagnosis and Treatment of Hepatocellular carcinoma
2. Cell Cycle in Cancer Cell
3. MicroRNA and liver diseases

Honors and Awards

• 1996：Award from Japanese Society of Hepatology
• 2004: Award from liver Forum in Kyoto
• 2006: Award from liver Forum in Kyoto
• Research ethics/ GCP training or experience:

Editorial experience

• Hepatology Research (Official journal of JSH)
• Associate Editor (2014-2018)

Educational and Career Experiences

• 1971-1976 Nagoya City University Medical School, Nagoya, Japan.
• 1981-1983 Gastroenterologist, Department of Gastroenterology, Chukyo Hospital, Nagoya, Japan.
• 1984-1986 Researcher, Under Prof. Gojobori, National Institute for Genetics, Mishima, Japan.
• 1990-1991 Clinical Research Fellow, Liver Unit, King’s Collage Hospital, London, UK.
• 2000-2008 Professor, Department of Clinical and Molecular Informative Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
• 2008-2016 Director General, The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan.
• 2016-Present Director, Genome Medical Sciences Project, National Center for Global Health and Medicine, Ichikawa, Japan.

Main Research Area

• Molecular evolutionary analysis of host and pathogen and their clinical application

Education/Post Graduate Training:

University:

• 1978-1984 MD, Faculty of Medicine, University of Tokyo
• 1995 PhD in Medicine, University of Tokyo Postgraduate School of Medicine

Residency:

• 1984-1986 Resident in University of Tokyo Hospital
• 1986-1989 Clinical Fellow in First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
• 1990-1994 Clinical Fellow in First Department of Internal Medicine, Faculty of Medicine, University of Tokyo

Present Position or Academic Rank:

• Professor: Faculty of Medicine, Saitama Medical University
• Chairman: Department of Gastroenterology & Hepatology, Saitama Medical University Hospital

Previous Professional Positions and Appointments:

• 1989-1990 Assistant Professor; First Department of Internal Medicine, University of Tokyo
• 1994-1995 Assistant Professor; Third Department of Internal Medicine, Saitama Medical University
• 1995-1998 Senior Lecture; Third Department of Internal Medicine, Saitama Medical University
• 1998-2003 Associate Professor; Third Department of Internal Medicine, Saitama Medical University
• 2003-2005 Professor; Department of Gastroenterology & Hepatology, Saitama Medical University
• 2005-present Professor and Chairman; Department of Gastroenterology & Hepatology, Saitama Medical University

Hospital:

• 1986-1987 Staff of Internal Medicine, Kodaira Memorial Tokyo Hitachi Hospital

Honors and Awards:

• 1992 Research Award from the Japan Society of Hepatology
• 2004 Research Award from the Liver Forum (Eastern Branch)

Professional and Society memberships:
Fellowship:

• The Japanese Society of Internal Medicine
• The Japan Society of Hepatology: JSH,
• The Japanese Society of Gastroenterology: JSFE

Membership and Position:

• American Association for the Study of Liver Diseases (AASLD); Member
• The Japanese Society of Internal Medicine; Supervisor, Previous Director
• The Japan Society of Hepatology (JSH): Director
• The Japanese Society of Gastroenterology (JSGR): Director
• The Japan Society for Portal Hypertension: Director
• The Japan Liver Transplantation Society: Executive Secretary

Educational Activities:

• 2008-2014 Associate Editor of KANZO
• 2011-2017 Associate Editor of Journal of Gastroenterology
• 2012-2014 Associate Editor of Hepatology Research
• 2013-Present Associate Editor of Japanese Journal of Portal Hypertension

Areas of Interest

• Gastrointestinel surgery
• Colorectal cancer
• detection of early cancer

Educational and Career Experiences

• 1980- Resident in general surgery, Kyushu University Hospital, Fukuoka
• 1991- Research Fellow, Dana-Farber Cancer Institute, Harvard Medical School, USA
• 1998- Chairman Professor of Surgery, Medical Institute of Bioregulation, Kyushu University
• 2008- Chairman Professor of Surgery, Graduate School of Medicine, Osaka University
• 2018-present Chairman Professor of Surgery, Graduate School of Medicine, Kyushu University

Honors and Awards

• 2010 Medical Award of the Japan Medical Association
• 2013 Princess Takamatsu Cancer Research Fund Prizes
• 2019 The Mataro Nagayo Prize (Japanese Cancer Association)
• 2020 Distinguished Service Award (Society of Surgical Oncology, USA)

Faculty Appointment

• 2013- Professor and Chairman, Dept. of Gastroenterology and Endoscopy center
• 2007-2013 Clinical Professor, Dept. of Gastroenterology
• 2004-2007 Associate Professor, Dept. of Gastroenterology,
• 1997-2004 Assistant Professor, 2^nd Dept. of Internal Medicine,
• 1991-1996 Assistant Fellow, 2^nd Dept. of Internal Medicine, Oita Medical University

Education:

• 1977-1983 Hiroshima University School of Medicine, Hiroshima (M.D.)
• 1986-1990 Graduate School of Medicine, Oita Medical University (Ph.D.)

Internship:

• 1983-1984 2^nd Dept. of Internal Medicine, Oita Medical University

Fellowship:

• 1996 – 1997 Postdoctoral Fellow, Tissue Typing Laboratory, University of California, Los Angeles (UCLA), LA, USA

Memberships:

• Fellow, American college of Gastroenterology
• Councilor, Japanese Society of Gastroenterology
• Councilor, Japanese Society of Gastroenterological Endoscopy
• Councilor & Secretary, The Japanese Society for Helicobacter Research
• Councilor, Japanese Gastroenterological Association
• Certified Physician, The Japanese Society of Internal Medicine
• The Japanese Association for Infectious Disease
• Japanese Society of Chemotherapy
• Japan Pancreas Society
• Japan Biliary Association
• The Japanese Society of General Medicine

Major Research Interests:

1. Clinical Microbiology of Helicobacter pylori infection
2. Endoscopic surgery for Gastrointestinal Tract

Areas of Interest

• Liver Cirrhosis, Hepatocellular Carcinoma

Educational and Career Experiences

• MD, PhD: Faculty of Medicine, University of Tokyo
• 1983 Resident in the University of Tokyo Hospital and Tokyo Kosei Nenkin Hospital
• 1998 Assistant Professor in Saitama Medical University
• 2004 Associate Professor in Saitama Medical University
• 2007 Professor of the Department of Gastroenterology & Hepatology, Saitama Medical University
• 2012 Professor of the Department of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University
• 2019 Director of the Department of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University

Honors and Awards

• SHISEIKAI Scientific Award

Areas of Interest

• Pathogenesis of viral hepatitis and hepatocellular carcinoma

Educational and Career Experiences

• 1989 M.D., Kanazawa University School of Medicine, Japan
• 1993 Ph.D. (Dr. of Medical Science), Kanazawa University, Japan
• 1994 Research Associate, The Scripps Research Institute (Prof. Francis V. Chisari), U.S.A.
• 1996 Assistant Professor, First Department of Internal Medicine, Kanazawa University School of Medicine, Japan
• 1997 Research Advisor, Monbusho (the Japanese Government) Research Experience Fellowships for Young Foreign Researchers, Japan
• 2011 Professor and Head, Second Department of Internal Medicine (Gastroenterology and Neurology), Faculty of Medical Sciences, University of Fukui, Japan

Honors and Awards

• 2004 GlaxoSmithKline Award, The 8th General Meeting of Japan Society of Hepatology, DDW-Japan, Fukuoka, Japan
• 1998 HANS POPPER PRIZE, International Association for the Study of the Liver (IASL) Biennial Scientific Meeting, Chicago, U.S.A.
• 1996 American Liver Foundation (ALF) FELLOW RESEARCH PRIZE, the 47th American Association for the Study of Liver Diseases (AASLD) Annual Meeting, Chicago, U.S.A.
• 1996 Young Investigator Award for the Research Workshop, the 47th AASLD Annual Meeting, Chicago, U.S.A.
• 1995 Postdoctoral Fellowship, Uehara Memorial Foundation, Tokyo, Japan
• 1992 Subsidy, the 1992 meeting on the molecular biology of hepatitis B virus, La Jolla, CA, U.S.A.

Education

• 1983 Graduated from Nagasaki University, School of Medicine
• 1991 Ph. D. of Medical Science from Nagasaki University

Appointments

• 1983-1984 Trainee, First Department of Internal Medicine, Nagasaki University School of Medicine
• 1984-1985 Trainee, Department of Internal Medicine, Nagasaki Municipal Hospital
• 1985-1986 Department of Internal Medicine, Tagawa Municipal Hospital
• 1986-1987 Department of Medicine, National Hospital Organization Saga National Hospital
• 1987 Medical Staff, Department of First Internal Medicine, Nagasaki University School of Medicine
• 1987-1990 Researcher, Department of Biochemistry, Calgary University of Medicine, Canada
• 1990-1992 Researcher, Department of First Internal Medicine, Nagasaki University of Medicine
• 1992-1994 Vice Chair, Department of Internal Medicine, The Japanese Red Cross Nagasaki Genbaku Hospital
• 1994-1998 Assistant, Department of First Internal Medicine, Nagasaki University of Medicine
• 1998-2002 Lecturer, Nagasaki University Health Center
• 2002-2006 Assistant Professor, Nagasaki University Health Center
• 2006-2009 Assistant Professor, Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences
• 2009- Professor, Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences
• 2015- Vice Director, Nagasaki University Hospital

Areas of Interest

• Hepatocellular carcinoma, Epigenetics, Genomics, Chromosome, Tumor suppressor gene, Molecular Biology, Artificial Intelligence, Data base science

Educational and Career Experiences

• 1996-1997: Researcher, Research Institute for Production Development
• 1997-2004: Assistant Professor, Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
• 2004-2006: Research Fellow, Division of Gastroenterology, Baylor University Medical Center
• 2006-2011: Assistant Professor/Lecture, Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine
• 2011-present: Associate Professor, Department of Gastroenterology and Hepatology, Fuculty of Medicine Kindai University

Honors and Awards

• 1993: Research Award, Japan Society of Hepatology
• 1994: Research Award, Hamanako Symposium
• 2003: The best Award for Clinical Science, The Kyoto conference for Adult disease
• 2008: Japan Society of Hepatology-Kanmuri Award, CHUGAI Award
• 2009: Presidential Award for the 45th Meeting, Japan Society of Hepatology

Areas of Interest

• Viral Hepatitis, Liver cirrhosis, Sarcopenia

Educational and Career Experiences

• 1981 MD, Osaka City University
• 1986 Ph.D, Osaka City University
• 2000-2005, Associate Professor, Osaka City University
• 2005-2020, Chief Professor, Hyogo College of Medicine
• 2013-2020, Vice President, Hyogo College of Medicine
• 2020-, Honorary Director, Kano General Hospital

Honors and Awards

• 1991 Research Encouragement Award of Japanese Society of Hepatology
• 1995 Kanae Medical Award
• 2018, President, the 54th. Annual Meeting of Japan Society of Hepatology
• 2019, President, the 22th. Annual Meeting of the Japanese Society of Geriatric Gastroenterology

Areas of Interest

• Hepatobiliary pancreatic (HBP) surgery for both benign and malignant diseases
• adult liver transplantation
• HBP surgical pathology

Educational and Career Experiences

He graduated from School of Medicine, Chiba University in 1988. After receiving general surgery training at Department of General Surgery, Chiba University Hospital and affiliated hospitals, he entered Graduate School of Medicine, Chiba University and majored surgical pathology at Department of Molecular Pathology under Professor Kondo. He had been to Belgium as a research fellow from 1996 to 2000 under Professor Pierre Gianello, Department of Experimental Surgery at Louvain Catholic University. He returned to Department of General Surgery, Chiba University in 2000 as a staff under Professor Masaru Miyazaki, and promoted to Professor and Chairman in 2016.

He has been an active member in many surgical and HBP societies. He is currently an Associate editor for Journal of Hepato-Biliary-Pancreatic Sciences (JHBPS).

Past Position:

Residency Trainee:
• Department of Internal Medicine, School of Medicine, Keio University, 1981-1986
Trainee:
• Department of Internal Medicine, Tokyo Metropolitan Ohkubo Hospital, 1986-1987
• Department of Internal Medicine, Tokyo Metropolitan Ohtsuka Hospital, 1987-1988
Instructor:
• Department of Internal Medicine, School of Medicine, Keio University, 1988-1991
• Assistant Professor Department of Internal Medicine, School of Medicine, Keio University, 1991-2008
Post-Doctoral Research Fellow
• Jefferson Cancer Institute, Thomas Jefferson University, Philadelphia, 1993-1994
Associated Professor
• Keio University, Antiaging Gastroenterology, 2008-2010
Professor
• Keio University Faculty of Pharmacy, 2010-2020.

Education

• Yamaguchi University, School of Medicine, (1978-1984) (M.D. degree)

Residency

• Yamaguchi University Hospital (1984-1987)

Academic Appointments

• 1990-1993: Registar of First Department of Internal Medicine, Yamaguchi University, School of Medicine
• 1993-2002: Assistant Professor of First Department of Internal Medicine, Yamaguchi University
• 2002-2003: Lecturer of Department of Gastroenterology & Hepatology, Yamaguchi University
• 2004: Associate Professor of Gastroenterology & Hepatology
• 2005-Present: Professor and Chairman of Gastroenterology & Hepatology, Yamaguchi University
• 2012-2016: Dean of Faculty of Medicine Yamaguchi University
• 2014-: Visiting Professor of Imperial College of London (UK)
• 2016-: Director of regenerative medicine & cell therapy

Selected Papers (reviewed papers 313)

1. Sakaida I, et al. J Biol Chem. 1991 Jan 15;266(2):717-22.
2. Sakaida I, et al. Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice. Hepatology. 2004;40(6):1304-11.
3. Terai S, Sakaida I, et al. Improved liver function in patients with liver cirrhosis after autologous bone marrow cell infusion therapy. Stem Cells. 2006;24(10):2292-8.
4. Yamasaki T, Sakaida I et al . Deferoxamine for advanced hepatocellular carcinoma. N Engl J Med. 2011 Aug 11;365(6):576-8.
5. Sakaida I et al. Tolvaptan for improvement of hepatic edema: A phase 3, multicenter, randomized, double-blind, placebo-controlled trial. Hepatol Res. 2014;44(1):73-82.

Areas of Interest

• Gastroenterology
• especially Hepatology
• Liver Transplantation
• Primary Biliary Cirrhosis
• Hepatocellular Carcinoma
• Viral Hepatitis

Educational and Career Experiences

• 2019- Professor of General Medicine Center, Fukuoka University School of Medicine
• 2007-2013 Vice President of Fukuoka University Hospital
• 2000- Professor and Chairman of the Department of Gastroenterology and Medicine, Fukuoka University
• 1997-2000: Associate Professor of Internal Medicine Department, Kurume University School of Medicine
• 1994-1997: Assistant Professor of Internal Medicine Department, Kurume University School of Medicine
• 1985-1987: Research Associate at the Department of Internal Medicine of Yale University in USA (worked with Professor James L. Boyer)
• 1978-1982: Graduate School of Medicine, Kurume University, and received Ph.D. degree
• 1978: Graduated from Kurume University School of Medicine

Honors and Awards

• Distinguished Award ( Yasuzumi Memorial Award ) , Japanese Society for Clinical Molecular Morphology 2009

Areas of Interest

• Minimum-invasive treatment　(PEIT, RFA, TAE) for hepatic neoplasms.
• hepatic arterial infusion chemotherapy and enhanced ultrasonography.

Educational and Career Experiences

• I graduated at Toho university school of medicine in 1992.
• I worked at Tokyo university hospital during from 1992 to 2008.
• From 2008, I have been worked in kyoundo Hospital which is afferent hospital of Tokyo university hospital.

Education:

• 1981 M.D., Osaka University
• 1993 Ph. D., First Department of Medicine
  Osaka University
  Thesis: Studies on the Mechanisms of Primary Nonfunction of Graft after Liver Transplantation

Professional Experience:

• April 2018-Mar 2019 Vice President of Mie University
• April 2009-Mar 2011 Vice Director of Mie University Hospital
• April 2007-present Professor and Chairman, Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine
• Feb 2004-Mar 2007 Associate Professor, Department of Gastroenterology, Juntendo University School of Medicine
• April 1998-Jan 2004 Assistant Professor, Department of Gastroenterology, Juntendo University School of Medicine (Chairman: Prof. Nobuhiro Sato)
• 1989-1998 Senior Fellow, Osaka University School of Medicine
• 1987-1989 Postdoctoral Research Associate, Laboratory of Hepatobiology and Toxicology, Department of Pharmacology, University of North Carolina (Director: Prof. Ronald G. Thurman)
• 1986-1987 Senior Fellow, Osaka University School of Medicine
• 1982-1986 Senior GI & Hepatology Specialist, Department of Gastroenterology and Hepatology, Osaka Minami National Hospital
• 1981-1982 Resident, First Department of Medicine, Osaka University

Honors:

• 1992 Presidential Award, Annual Meeting of the Japan Society for Transplantation
• 2004 Otsuka Award, Japan Society of Hepatology "Targeted gene delivery to sinusoidal endothelial cells: DNA nanoassociate bearing hyaluronan-glycocalyx."

Professional Societies:

• Japanese Society of Internal Medicine
• Japan Society of Hepatology
• Japanese Society of Gastroenterology
• Japan Society for Transplantation
• Japan Gastroenterological Endoscopy Society
• Transplantation Society
• American Association for the Study of Liver Diseases
• American Gastroenterological Association (AGAF)

Editorial Boards:

• 1991-1996 Nanzando's Textbook of Internal Medicine
• 2004-2007 Editorial Board: Journal of Gastroenterology and Hepatology
• 2010- Editorial Board: Hepatology Research
• 2015- Journal of Gastroenterology

ORIGINAL ARTICLES:

1. Increase in survival time of liver transplants by protease inhibitors and a calcium channel blocker, nisoldipine. Transplantation 1990; 50: 14-20.
2. Leukocyte adhesion and cell death following orthotopic liver transplantation in the rat. Transplantation 1991; 51: 959-965.
3. Carolina rinse solution: A new strategy to increase survival time after orthotopic liver transplantation in the rat. Transplantation 1991; 52: 417-424.
4. Tumor necrosis factor and endotoxin are involved in the pathogenesis of liver and pulmonary injuries following orthotopic liver transplantation in the rat. Hepatology 1992; 16: 487-493.
5. Roles of endothelin-1 and nitric oxide in the mechanism for ethanol-induced vasoconstriction in rat liver. J. Clin. Invest. 1993; 91: 1337-1342.
6. Vasoactive effect of endothelin-1 on rat liver in vivo. Hepatology 1994; 19: 155-161.
7. Leptin receptor-mediated signaling regulates profibrogenic responses and remodeling of extracellular matrix in the rat liver. Gastroenterology 2002; 122: 1399-1410.
8. Thalidomide Prevents Alcoholic Liver Injury in Rats through Suppression of Kupffer Cell Sensitization and TNF-Production. Gastroenterology, 2002; 123:291-300.
9. Dietary Glycine prevents colitis induced by 2,4,6-trinitrobensene sulphonic acid in the rat. Gastroenterology 2003; 125: 775-785.
10. Targeted gene delivery to sinusoidal endothelial cells: DNA nanoassociate bearing hyaluronan-glycocalyx. FASEB J. 2004; 18: 699-701 (10.1096/fj.03-0494fje, published on line February 20, 2004).

Areas of Interest

• Diagnosis and Treatment of Hepatocellular Carcinoma

Educational and Career Experiences

Dr. Masatoshi Tanaka graduated Kurume university school of medicine in 1979, and received his PhD degree in Medical Science in 1989. His profession is a diagnosis and treatment of hepatocellular carcinoma (HCC). He started his carrier of percutaneous ethanol injection (PEI) from 1985, intra-arterial embolo-therapy and chemotherapy from 1989, and radiofrequency ablation from 1998. He was a director at the Dept. of Gastroenterology and Hepatology, Kurume University Medical Center, and is now a director of Hepatology and Clinical Research Center, Yokokura hospital since 2012. He is a board member of Liver Cancer Study Group of Japan, Japanese Society of Gastraenterology, Hepatology and Ultrasonics in medicine, and also a director board member of Asian Conference on Tumor Ablation, and organized 2nd ACTA meeting in 2015.

Dr. Ryosuke Tateishi graduated from the University of Tokyo in 1995. On completion of clinical fellowship at the University of Tokyo Hospital and Mitsui Memorial Hospital, he started his PhD in hepatology at the University of Tokyo in 1998. During his PhD, he studied the prognostic factors of patients with HCC and developed a new scoring system named Tokyo Score.
After his PhD graduation, he became an attending staff at the Department of Gastroenterology, the University of Tokyo Hospital in 2002.
Then he served as a chief physician at the Department of Gastroenterology of Mitsui Memorial Hospital from 2005 to 2006.
He was an Assistant Professor at the Department of Gastroenterology of the University of Tokyo Hospital from 2006 to 2013.
Since 2013, he has been a Project Associate professor at the Department of Gastroenterology, the University of Tokyo Hospital where he continues working on diagnosis and treatment of HCC, particularly on those who underwent percutaneous treatment.
He is currently a member of the Committee for the General Rules for the Clinical and Pathological Study of Primary Liver Cancer in Liver Cancer Study Group of Japan. He also has been served on a member of three guideline committees: Japanese Clinical Practice Guideline for Liver Cancer, Asian Pacific Association for the Study of the Liver (APASL) hepatocellular carcinoma guideline, and Asian Conference on Tumor Ablation (ACTA) guideline.
He published more than 150 international scientific papers in high-quality English Journal including Gastroenterology, Hepatology, Gut, and Journal of Hepatology. He has also served as an associate editor in Hepatology Research.

Educational and Career Experiences

Education:
• 1982 MD Keio University School of Medicine, Tokyo (270184)
• 1991 PhD Keio University School of Medicine, Tokyo (2308) Academic Appointments:
• 1988-1990 Research Fellow, Department of Surgery, Harvard Medical School and Massachusetts General Hospital, Boston
• 1993-2001 Instructor in Surgery, Keio University School of Medicine, Tokyo
• 2001-2005 Assistant Professor in Surgery, Keio University School of Medicine, Tokyo
• 1993-2005 Chief, Transplantation Biology Section, Division of Transplantation, Department of Surgery, Keio University School of Medicine, Tokyo
• 1997-2005 Visiting Scientist, Department of Molecular Biology, Keio University School of Medicine, Tokyo
• 2005- 2015 Professor and Chairman, Department of Surgery, Iwate Medical University School of Medicine, Iwate
• 2015- 2016 Senior consultant, Department of Surgery, Ageo Central General Hospital, Saitama
• 2016-2017 Director, Center for Advanced Treatment of Hepatobiliary and Pancreatic Diseases, and Chief, Surgical Services, Ageo Central General Hospital, Saitama
• 2017- Director, Center for Advanced Treatment of Hepatobiliary and Pancreatic Diseases, and Chief, Surgical Services, Deputy Director, Ageo Central General Hospital, Saitama

Honors and Awards

• 1988 Uehara Memorial Foundation Award
• 1994 German Surgical Society Fellowship
• 1994 The Keio Medical Science Award
• 1995 Sakaguchi Memorial Award – Keio University School of Medicine
• 1996 Kanae Young Investigator Award
• 1996 Gold Medal for Video Olympics- The World Congress of Endoscopic Surgery
• 1997 Second Prize Award-The Society of American Gastrointestinal Endoscopic Surgeons
• 1998 Young Investigator Award-Japan Gene Therapy Foundation

Areas of Interest

• Treatment of liver tumor

Educational and Career Experiences

• 1993 Graduated from Osaka University
• 2000 Graduated from Graduated school of medicine, University of Tokyo
• 1993 University of Tokyo hospital
• 1994 Toranomon hospital
• 1996 University of Tokyo hospital
• 2001 JR Tokyo general hospital
• 2003 University of Miami
• 2005 University of Tokyo hospital
• 2008 Japanese Red Cross Medical Center

Areas of Interest

• Liver cirrhosis
• Liver fibrosis
• NASH

Educational and Career Experiences

• - 1993: Ph.D. (Medical Science), Graduate School of Nara Medical University
• 1994~1997: Visiting Fellow, NIH, National Cancer Institute, USA
• 1999: Assistant Professor, Third Department of Internal Medicine, Nara Medical University
• 2015: Chairman and Full Professor

• Director of Japanese Society of Hepatology (JSH)
• Chairman of clinical practice guideline for liver cirrhosis of JSGE/JSH
• Founding member of ILCA (International Liver Cancer Association)
• International active member of EASL, AASLD, AACR
• Active member of NYAS (New York Academy of Science)
• Deputy Editor-in Chief: Hepatology Research
• Associate Editor-in Chief: World Journal of Gastroenterology
• AE in other 14 international Journals

Honors and Awards

• 1998: UICC (International union against cancer) Young investigator award
• 1999, 2000: Award of Japanese Society of Hepatology
• 2001: Award of Japanese Association for Metastasis Research
• 2003: Award of Nara Medical University
• 2004: Award of Japanese Hepatology Research

Education

• 1980/1986: The University of Tokyo Undergraduate Program

Post Graduate Training

• 1986/1998: The University of Tokyo Postgraduate Program
• 1998/1990: Toshiba General Hospital Gastroenterology Program

Certifications

• 1995: M.D. (molecular virology of hepatitis A virus)

Professional Appointments

• 1995: Assistant Professor (The University of Tokyo Hospital)
• 1998: Associate Professor (St. Marianna University School of Medicine)
• 2004: Associate Professor (The University of Tokyo Hospital, Dept. of Infection Control and Prevention)
• 2008: Associate Professor (The University of Tokyo, Dept. of Infectious Diseases)
• 2010: Chief of the Department
• 2018: Professor (Division of Infectious Diseases, Advanced Clinical Research Center, The Institute of Medical Science, the University of Tokyo)